Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6583092 | 0.99 | KCNH2 (0.42) | KCNH2MAOBPTPN1SMPD1HRH3 | |
| SCHEMBL6577701 | 0.85 | SMPD1 (0.55) | SMPD1 | |
| Hydrochloric Acid SCHEMBL6579984 | 0.85 | SMPD1 (0.54) | SMPD1 | |
| SCHEMBL6580042 | 0.83 | DRD1 (0.48) | SMPD1SIGMAR1 | |
| SCHEMBL6579435 | 0.83 | SIGMAR1 (0.40) | KCNH2MAOBSMPD1HRH3SIGMAR1 | |
| SCHEMBL6581800 | 0.81 | CYP3A4 (0.48) | SMPD1 | |
| Hydrochloric Acid SCHEMBL6581834 | 0.81 | BLM (0.49) | KCNH2SMPD1 | |
| SCHEMBL6582164 | 0.79 | HTR2A (0.43) | MAOBMAOA | |
| SCHEMBL6582459 | 0.78 | KCNH2 (0.55) | KCNH2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6582237 | 0.78 | HTR2A (0.42) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737680-B1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-5679699-A | ANTIISCHEMIC AGENTS, HEART RATE LOWERING AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1997-10-21 | — | — | US | disclosed |
| EP-0737680-A1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1996-10-16 | — | — | EP | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |