Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584670 | 0.84 | HTR1A (0.37) | HTR1A | |
| SCHEMBL6580878 | 0.82 | SCD (0.44) | HTR1A | |
| SCHEMBL6586188 | 0.79 | GRIN2B (0.41) | HTR1A | |
| SCHEMBL6580506 | 0.79 | BCHE (0.34) | — | |
| Hydrochloric Acid SCHEMBL6583478 | 0.77 | F10 (0.46) | — | |
| Hydrochloric Acid SCHEMBL6980263 | 0.72 | MAPT (0.46) | — | |
| SCHEMBL6584671 | 0.71 | SMO (0.36) | — | |
| SCHEMBL6582418 | 0.71 | SMO (0.40) | — | |
| SCHEMBL6986879 | 0.69 | KMT2A (0.42) | — | |
| SCHEMBL6581653 | 0.69 | HTR1A (0.37) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |