Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580506 | 0.94 | BCHE (0.34) | — | |
| SCHEMBL6581653 | 0.85 | HTR1A (0.37) | HTR1A | |
| SCHEMBL6580878 | 0.84 | SCD (0.44) | HTR1A | |
| SCHEMBL6582525 | 0.84 | HTR1A (0.40) | HTR1A | |
| SCHEMBL6582799 | 0.82 | CCNT1 (0.38) | — | |
| SCHEMBL6583196 | 0.78 | BRD4 (0.38) | — | |
| SCHEMBL6582400 | 0.78 | SCD (0.41) | — | |
| SCHEMBL6582672 | 0.76 | GRIN2B (0.39) | — | |
| SCHEMBL6582859 | 0.75 | GRIN2B (0.46) | — | |
| SCHEMBL6581263 | 0.74 | SCD (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |