Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.45 |
| ▸ | CTSL | P07711 | 12/20 | 0.45 |
| ▸ | CTSS | P25774 | 8/20 | 0.45 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580369 | 0.85 | CTSK (0.44) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6582315 | 0.82 | CTSK (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6582309 | 0.79 | CTSK (0.44) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6582321 | 0.75 | CTSK (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6578303 | 0.72 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6578050 | 0.72 | CTSK (0.81) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577961 | 0.70 | CTSK (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577997 | 0.70 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7379929 | 0.69 | CTSK (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5099108 | 0.68 | CTSK (0.51) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |