Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.44 |
| ▸ | CTSL | P07711 | 10/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582315 | 0.87 | CTSK (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6578303 | 0.86 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6581006 | 0.85 | SIGMAR1 (0.43) | CTSKSIGMAR1 | |
| SCHEMBL6582321 | 0.80 | CTSK (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6582644 | 0.79 | CTSK (0.45) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577997 | 0.77 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580052 | 0.75 | CTSK (0.69) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6583959 | 0.73 | CTSK (0.52) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580739 | 0.73 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| Lithium Ion SCHEMBL6582305 | 0.72 | CTSK (0.53) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |
| EP-0936912-A4 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 1999-10-13 | — | — | EP | disclosed |
| EP-0936912-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998005336-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | disclosed |