Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582630 | 0.87 | MEN1 (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6577282 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6579996 | 0.83 | HSP90AA1 (0.38) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6582508 | 0.78 | EDNRA (0.43) | EDNRAEDNRBALDH1A1 | |
| SCHEMBL6580208 | 0.77 | EDNRB (0.45) | EDNRAEDNRB | |
| SCHEMBL6308654 | 0.76 | EDNRB (0.55) | EDNRAEDNRBALDH1A1 | |
| SCHEMBL8543285 | 0.75 | EDNRB (0.69) | EDNRAEDNRBALDH1A1 | |
| SCHEMBL6577691 | 0.73 | MEN1 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17140162 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL8329557 | 0.73 | MEN1 (0.39) | EDNRAEDNRBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804435-B1 | NOVEL IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2004-03-10 | — | — | EP | claimed |
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | claimed |
| CN-1159805-A | Nvel imidazole derivatives, method for preparing same, novel intermediates thus obtained, medicinal applications of same and pharmaceutical compositions containing same | ROUSSEL UCLAF (FR) | 1997-09-17 | — | — | CN | claimed |
| CN-1083838-C | Nvel imidazole derivatives, method for preparing same, novel intermediates thus obtained, medicinal applications of same and pharmaceutical compositions containing same | ROUSSEL UCLEF (FR) | 2002-05-01 | — | — | CN | disclosed |
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |
| CN-1159805-A | Nvel imidazole derivatives, method for preparing same, novel intermediates thus obtained, medicinal applications of same and pharmaceutical compositions containing same | ROUSSEL UCLAF (FR) | 1997-09-17 | — | — | CN | disclosed |