Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501148 | 0.85 | FNTA (0.35) | ALDH1A1MEN1ALOX15KMT2AKDM4E | |
| SCHEMBL30206854 | 0.83 | ALDH1A1 (0.56) | TAAR1ALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL21071359 | 0.81 | DDB1 (0.47) | TAAR1ALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL4828614 | 0.81 | TAAR1 (0.56) | TAAR1ALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL12404795 | 0.78 | EPHX2 (0.34) | TAAR1ALDH1A1MEN1KMT2ATRPM5 | |
| Hydrochloric Acid SCHEMBL5849987 | 0.76 | SIGMAR1 (0.50) | ALDH1A1MEN1ALOX15KMT2AUSP2 | |
| SCHEMBL12404781 | 0.75 | BRD4 (0.35) | TAAR1ALDH1A1MEN1ALOX15KMT2A | |
| SCHEMBL14106010 | 0.75 | DDB1 (0.32) | HTR2C | |
| SCHEMBL18322642 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1ALOX15KMT2AUSP2 | |
| SCHEMBL2962004 | 0.72 | MEN1 (0.42) | ALDH1A1MEN1ALOX15KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138207-A1 | Anticancer agents; side effect reduction | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1391203-A1 | ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138207-A1 | Anticancer agents; side effect reduction | MKI67, TPMT, PBRM1 | TAAR1 1968/4885ALDH1A1 505/4885MEN1 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.