Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426336 | 0.92 | NPC1 (0.55) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| Phenol SCHEMBL27301947 | 0.86 | MAOA (0.52) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| 4-Aminophenol SCHEMBL7014541 | 0.86 | CA9 (0.57) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL28979239 | 0.81 | MAPT (0.53) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29946465 | 0.81 | MAPT (0.58) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6405990 | 0.81 | MAPT (0.58) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29533407 | 0.81 | CYP11B1 (0.62) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL16208500 | 0.78 | KIF11 (0.67) | TNIKCRBNKIF11 | |
| SCHEMBL8751 | 0.78 | CA9 (0.62) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29438605 | 0.78 | CA9 (0.62) | NPC1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311485-A4 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMA (IL) | 2004-05-12 | — | — | EP | claimed |
| EP-1311485-A1 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-05-21 | — | — | EP | claimed |
| US-20020099213-A1 | Processes for preparing cilostazol | TEVA PHARMACEUTICALS USA, INC. | 2002-07-25 | — | — | US | claimed |
| WO-2002014283-A1 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2002-02-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099213-A1 | Processes for preparing cilostazol | PDE3A, PDE12, PDE5A | NPC1 1826/4885MAPK13 2369/4885MAPK12 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.