Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.74 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.72 |
| ▸ | DRD2 | P14416 | 5/20 | 0.67 |
| ▸ | DRD4 | P21917 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.67 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.67 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161133 | 0.87 | CHRM1 (0.92) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL11179730 | 0.87 | OPRM1 (0.72) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL19358801 | 0.87 | OPRM1 (1.00) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL3665096 | 0.86 | OPRM1 (1.00) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL22298693 | 0.84 | OPRM1 (0.67) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL4919890 | 0.82 | OPRM1 (0.65) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL8863592 | 0.82 | CHRM1 (0.61) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| Oxalic Acid SCHEMBL5778025 | 0.81 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL8863557 | 0.81 | OPRM1 (0.91) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| SCHEMBL8349502 | 0.81 | OPRM1 (0.61) | OPRM1OPRK1OPRL1CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |