Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583243 | 1.00 | TRPA1 (0.48) | TRPA1MTNR1AMAPTKDRALDH1A1 | |
| SCHEMBL6583466 | 0.96 | MAPT (0.47) | TRPA1MTNR1AMAPTKDRALDH1A1 | |
| SCHEMBL6583468 | 0.96 | MAPT (0.47) | TRPA1MTNR1AMAPTKDRALDH1A1 | |
| SCHEMBL6583866 | 0.96 | MAPT (0.48) | TRPA1MTNR1AMAPTKDRALDH1A1 | |
| SCHEMBL6157314 | 0.91 | ALDH1A1 (0.54) | MAPTKDRALDH1A1FFAR1KDM4E | |
| SCHEMBL6584383 | 0.90 | MAPT (0.46) | TRPA1MTNR1AMAPTKDRALDH1A1 | |
| SCHEMBL8888136 | 0.90 | TRPA1 (0.52) | TRPA1MTNR1APPARGPPARAPPARD | |
| SCHEMBL8888142 | 0.90 | TRPA1 (0.52) | TRPA1MTNR1APPARGPPARAPPARD | |
| SCHEMBL6587325 | 0.89 | PPARG (0.46) | MAPTKDRFFAR1KDM4EPPARG | |
| SCHEMBL6584308 | 0.89 | KDR (0.45) | MAPTKDRFFAR1KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |