Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 18/20 | 0.51 |
| ▸ | PPARA | Q07869 | 17/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888142 | 1.00 | TRPA1 (0.52) | TRPA1MTNR1APPARGPPARAPTPN2 | |
| SCHEMBL5760923 | 0.91 | NPC1 (0.54) | PPARGPPARAPTPN2PTPN1PPARD | |
| SCHEMBL6583241 | 0.90 | TRPA1 (0.48) | TRPA1MTNR1APPARGPPARAPTPN2 | |
| SCHEMBL6583243 | 0.90 | TRPA1 (0.48) | TRPA1MTNR1APPARGPPARAPTPN2 | |
| SCHEMBL8887495 | 0.87 | PPARG (0.49) | PPARGPPARAPTPN2PTPN1PPARD | |
| SCHEMBL6583466 | 0.86 | MAPT (0.47) | TRPA1MTNR1APPARGPPARAPTPN2 | |
| SCHEMBL6583468 | 0.86 | MAPT (0.47) | TRPA1MTNR1APPARGPPARAPTPN2 | |
| SCHEMBL6583866 | 0.86 | MAPT (0.48) | TRPA1MTNR1APPARGPPARAPTPN2 | |
| SCHEMBL8888616 | 0.85 | FDPS (0.64) | PPARGPPARAPPARD | |
| SCHEMBL8888613 | 0.85 | FDPS (0.64) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |