Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197663 | 0.82 | CYP1A2 (0.33) | CYP1A2CYP2A6 | |
| SCHEMBL31670075 | 0.78 | CYP2A6 (0.52) | CYP1A2CYP2A6 | |
| SCHEMBL645480 | 0.76 | CYP1A2 (0.55) | CYP1A2CYP2A6 | |
| SCHEMBL2251601 | 0.72 | NQO1 (0.43) | CYP1A2 | |
| SCHEMBL23413070 | 0.70 | CYP3A4 (0.51) | CYP1A2 | |
| SCHEMBL15298750 | 0.69 | CYP1A2 (0.50) | CYP1A2CYP2A6 | |
| SCHEMBL28166206 | 0.69 | UGT2B7 (0.41) | CYP1A2 | |
| SCHEMBL7199090 | 0.69 | CYP1A2 (0.33) | CYP1A2CYP2A6 | |
| SCHEMBL5543057 | 0.69 | GPR3 (0.40) | CYP1A2 | |
| SCHEMBL6417161 | 0.69 | HTR2A (0.35) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414788-A1 | NAPHTHYLUREA AND NAPHTHYLACETAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) ANTAGONISTS | Bayer HealthCare AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003014064-A1 | NAPHTHYLUREA AND NAPHTHYLACETAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2003-02-20 | — | — | WO | disclosed |