Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.50 |
| ▸ | PDE4A | P27815 | 5/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583476 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL22713946 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL6883557 | 0.83 | ALDH1A1 (0.66) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL7560477 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL70835 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL29808190 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL13522989 | 0.82 | ALDH1A1 (0.68) | ALDH1A1TSHRPDE4BTTRFDPS | |
| SCHEMBL4637156 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL498539 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL7361245 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRPDE4BPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |