Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 12/20 | 0.52 |
| ▸ | MAOB | P27338 | 12/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585754 | 0.97 | DRD2 (0.56) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6583194 | 0.96 | DRD2 (0.60) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6586944 | 0.95 | MAOA (0.58) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6585295 | 0.94 | MAOA (0.59) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6584813 | 0.94 | MAOA (0.60) | DRD2MAOAMAOB | |
| SCHEMBL6589109 | 0.93 | DRD2 (0.62) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6585123 | 0.92 | MAOA (0.61) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL8308852 | 0.91 | DRD2 (0.54) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6588613 | 0.91 | MAOA (0.61) | DRD2HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6584570 | 0.91 | MAOA (0.63) | DRD2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |