Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967428 | 0.88 | ALDH1A1 (0.43) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL6583521 | 0.87 | HDAC1 (0.43) | HDAC1HDAC6MTNR1AMTNR1BMEN1 | |
| SCHEMBL8337135 | 0.85 | MEN1 (0.39) | HDAC1HDAC6MTNR1AMTNR1BMEN1 | |
| SCHEMBL8340545 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL6960498 | 0.84 | HDAC1 (0.45) | HDAC1HDAC6MTNR1AMTNR1BMEN1 | |
| SCHEMBL6583517 | 0.81 | PPARG (0.56) | HDAC1HDAC6MTNR1AMTNR1BMEN1 | |
| SCHEMBL6969226 | 0.80 | FFAR1 (0.41) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL6975089 | 0.78 | PPARG (0.39) | HDAC1HDAC6MTNR1AMTNR1BMEN1 | |
| SCHEMBL8341338 | 0.78 | PPARG (0.41) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL4727181 | 0.76 | PPARG (0.54) | MTNR1AMTNR1BKMT2AMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |