Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889117 | 0.93 | GAA (0.42) | GAAALDH1A1KDM4ETSHRPIM1 | |
| SCHEMBL6581895 | 0.88 | TAAR1 (0.50) | GAAALDH1A1TSHRTDP1 | |
| SCHEMBL6583689 | 0.81 | SIRT2 (0.45) | GAAALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6583033 | 0.81 | MTNR1A (0.48) | GAAALDH1A1TSHRTDP1 | |
| SCHEMBL6584139 | 0.81 | CYP3A4 (0.49) | GAATSHRKMT2AMAPTMEN1 | |
| SCHEMBL6581977 | 0.80 | MTNR1A (0.47) | GAAALDH1A1TSHRTDP1 | |
| SCHEMBL6583789 | 0.76 | GAA (0.46) | GAAALDH1A1KDM4ETSHRPIM1 | |
| SCHEMBL8888947 | 0.75 | ESR1 (0.41) | GAAALDH1A1KDM4EKMT2ATDP1 | |
| SCHEMBL8889642 | 0.74 | APP (0.44) | GAAALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6583549 | 0.73 | SIRT2 (0.56) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |