Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584906 | 0.99 | PDK2 (0.50) | PDK2PDK4PDK1PDK3DDB1 | |
| SCHEMBL6585179 | 0.96 | PDK2 (0.53) | PDK2PDK4PDK1PDK3DDB1 | |
| SCHEMBL10828304 | 0.82 | PDK2 (0.61) | PDK2PDK4PDK1PDK3PGR | |
| SCHEMBL10917981 | 0.80 | PGR (0.38) | DDB1CRBNHTTPGRPRKCA | |
| SCHEMBL10828347 | 0.77 | PDK2 (0.57) | PDK2PDK4PDK1PDK3PGR | |
| SCHEMBL6587508 | 0.76 | PDK2 (0.34) | PDK2PDK4PDK1PDK3DDB1 | |
| SCHEMBL6585907 | 0.75 | PDK2 (0.33) | PDK2PDK4PDK1PDK3DDB1 | |
| SCHEMBL6583214 | 0.74 | PDK2 (0.41) | PDK2PDK4MAOBHTTPGR | |
| SCHEMBL6582041 | 0.71 | PDK2 (0.35) | PDK2PDK4PDK1PDK3HTT | |
| SCHEMBL2269040 | 0.70 | PDK2 (0.61) | PDK2PDK4PDK1PDK3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |