Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.32 |
| ▸ | PDE5A | O76074 | 3/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 4/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585907 | 0.99 | PDK2 (0.33) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL6582041 | 0.96 | PDK2 (0.35) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL6588788 | 0.93 | PDK2 (0.35) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL8557765 | 0.80 | PDK2 (0.32) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL8557766 | 0.80 | PDK2 (0.32) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL8557014 | 0.77 | PDK2 (0.33) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL6583855 | 0.76 | PDK2 (0.51) | PDK2ALDH1A1HTTDDB1CRBN | |
| SCHEMBL6584906 | 0.75 | PDK2 (0.50) | PDK2ALDH1A1HTTDDB1CRBN | |
| SCHEMBL6584999 | 0.74 | PDK2 (0.36) | PDK2ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL6583214 | 0.72 | PDK2 (0.41) | PDK2ALDH1A1KMT2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |