Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26930302 | 0.87 | GPR119 (0.42) | L3MBTL1LMNAGPR119BACE1RORC | |
| SCHEMBL23291555 | 0.87 | USP30 (0.48) | L3MBTL1GPR119BACE1RORCESR2 | |
| SCHEMBL653589 | 0.85 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2AESR2 | |
| SCHEMBL16874616 | 0.85 | L3MBTL1 (0.50) | L3MBTL1LMNAGPR119BACE1MEN1 | |
| SCHEMBL31549191 | 0.85 | NR1H2 (0.53) | L3MBTL1LMNAGPR119MEN1KMT2A | |
| SCHEMBL29041998 | 0.85 | BACE1 (0.43) | L3MBTL1GPR119BACE1RORCESR2 | |
| SCHEMBL1811376 | 0.83 | L3MBTL1 (0.48) | L3MBTL1LMNAGPR119MEN1KMT2A | |
| SCHEMBL17586447 | 0.82 | L3MBTL1 (0.42) | L3MBTL1GPR119BACE1RORCESR2 | |
| SCHEMBL3249913 | 0.82 | OPRD1 (0.49) | L3MBTL1GPR119PDK2 | |
| SCHEMBL3540605 | 0.82 | EPHX2 (0.40) | L3MBTL1LMNAGPR119BACE1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |
| EP-1036062-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | Pfizer Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029667-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |