⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657569 | 0.83 | PGK1 (0.32) | — | |
| SCHEMBL658949 | 0.75 | IDO1 (0.32) | — | |
| SCHEMBL27038218 | 0.70 | PDPK1 (0.32) | — | |
| SCHEMBL31577531 | 0.68 | — | — | |
| SCHEMBL3644211 | 0.62 | XDH (0.41) | — | |
| SCHEMBL23967207 | 0.61 | TTR (0.33) | — | |
| SCHEMBL31473821 | 0.60 | — | — | |
| SCHEMBL1164963 | 0.59 | HTT (0.37) | — | |
| SCHEMBL25386878 | 0.59 | KMT2A (0.34) | — | |
| SCHEMBL14941507 | 0.59 | NNMT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| EP-2534156-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
| WO-2011100502-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2011-08-18 | — | — | WO | disclosed |