Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL6584038 | 0.82 | GRM2 (0.40) | GRM2POLBMAPTTP53KDM4E | |
| SCHEMBL8333267 | 0.79 | RAB9A (0.41) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL6584034 | 0.79 | GRM2 (0.45) | GRM2POLBMAPTTP53KDM4E | |
| SCHEMBL7796549 | 0.77 | GRM2 (0.45) | GRM2POLBMAPTTP53KDM4E | |
| SCHEMBL7590460 | 0.77 | DYRK1A (0.41) | GRM2POLBMAPTKDM4ETHRB | |
| SCHEMBL6584296 | 0.75 | KMT2A (0.40) | GRM2POLBMAPTKDM4EMEN1 | |
| SCHEMBL7047027 | 0.71 | MAPT (0.40) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL7793772 | 0.71 | DHODH (0.45) | POLBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8686701 | 0.71 | DHODH (0.40) | GRM2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7787062 | 0.71 | DYRK1A (0.51) | GRM2POLBMAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778947-B1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN INC (US) | 2004-05-12 | — | — | EP | disclosed |
| US-5686258-A | Chemiluminescent detection of hydrolytic enzymes using an acridan | LUMIGEN, INC. (US) | 1997-11-11 | — | — | US | disclosed |