Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.46 |
| ▸ | MAOA | P21397 | 12/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585088 | 0.99 | MAOB (0.47) | MAOBMAOAPDK2PDK4LMNA | |
| SCHEMBL6583879 | 0.94 | MAOB (0.48) | MAOBMAOAPDK2PDK4PGR | |
| SCHEMBL6584776 | 0.92 | MAOB (0.48) | MAOBMAOAPDK2PDK4PGR | |
| SCHEMBL6584678 | 0.89 | MAOB (0.58) | MAOBMAOAPDK2PDK4MMP2 | |
| SCHEMBL6584839 | 0.87 | MAOB (0.60) | MAOBMAOAPDK2PDK4PGR | |
| SCHEMBL6583303 | 0.83 | MAOB (0.61) | MAOBPDK2PDK4PGR | |
| SCHEMBL10829230 | 0.81 | MAOB (0.48) | MAOBPDK2PDK4LMNAMAPT | |
| SCHEMBL6583223 | 0.80 | MAOB (0.61) | MAOBPDK2PDK4PGR | |
| SCHEMBL10834397 | 0.77 | MAOB (0.54) | MAOBMAOAPDK2PDK4PGR | |
| SCHEMBL6000884 | 0.76 | MAOB (0.50) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |