Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 6/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583879 | 0.94 | MAOB (0.48) | MAOBPDK2PDK4PGRBMPR1B | |
| SCHEMBL6585088 | 0.93 | MAOB (0.47) | MAOBPDK2PDK4PGRBMPR1B | |
| SCHEMBL6584050 | 0.92 | MAOB (0.46) | MAOBPDK2PDK4PGRMAOA | |
| SCHEMBL6583223 | 0.88 | MAOB (0.61) | MAOBPDK2PDK4PGR | |
| SCHEMBL10829230 | 0.83 | MAOB (0.48) | MAOBPDK2PDK4PGRBMPR1B | |
| SCHEMBL6583303 | 0.82 | MAOB (0.61) | MAOBPDK2PDK4PGRATAD2 | |
| SCHEMBL6584839 | 0.81 | MAOB (0.60) | MAOBPDK2PDK4PGRMAOA | |
| SCHEMBL6584678 | 0.80 | MAOB (0.58) | MAOBPDK2PDK4PGRMAOA | |
| SCHEMBL4842368 | 0.78 | PGR (0.57) | MAOBPDK2PDK4PGRMAOA | |
| SCHEMBL30642204 | 0.78 | PGR (0.57) | MAOBPDK2PDK4PGRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |