Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 5/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583751 | 0.91 | SIGMAR1 (0.51) | HIF1AEPAS1SIGMAR1 | |
| SCHEMBL6586286 | 0.84 | PDE4B (0.45) | HIF1AEPAS1SIGMAR1 | |
| SCHEMBL6584261 | 0.84 | PDE4B (0.51) | HTR2CMAPK1HTR2AHTR2BALDH1A1 | |
| SCHEMBL7963965 | 0.82 | PDE4A (0.50) | — | |
| SCHEMBL6583426 | 0.81 | PDE4B (0.51) | — | |
| SCHEMBL6583354 | 0.81 | HIF1A (0.45) | HIF1AEPAS1HTR2CMAPK1SMN1; SMN2 | |
| SCHEMBL6583511 | 0.80 | PDE4B (0.44) | HIF1AEPAS1HTR2CSIGMAR1MAPK1 | |
| SCHEMBL6582719 | 0.80 | PDE4B (0.48) | — | |
| SCHEMBL6582911 | 0.80 | PDE4B (0.51) | HIF1AEPAS1HTR2CSMN1; SMN2ALDH1A1 | |
| SCHEMBL6585235 | 0.80 | HPGD (0.40) | HIF1AEPAS1HTR2CSMN1; SMN2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |