Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584488 | 1.00 | MAPK1 (0.50) | MAPK1PKMRAB9AKDM4EABCB1 | |
| SCHEMBL6584485 | 1.00 | MAPK1 (0.50) | MAPK1PKMRAB9AKDM4EABCB1 | |
| SCHEMBL6081086 | 0.87 | ABCB1 (0.52) | MAPK1PKMRAB9AKDM4EABCB1 | |
| SCHEMBL6080610 | 0.87 | ABCB1 (0.52) | MAPK1PKMRAB9AKDM4EABCB1 | |
| SCHEMBL6587318 | 0.84 | ALDH1A1 (0.66) | MAPK1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL6588460 | 0.84 | APP (0.59) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL6588463 | 0.84 | APP (0.59) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL6588464 | 0.84 | APP (0.59) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL6587311 | 0.84 | ALDH1A1 (0.66) | MAPK1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL6587315 | 0.84 | ALDH1A1 (0.66) | MAPK1RAB9AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |