Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587311 | 1.00 | ALDH1A1 (0.66) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6587318 | 1.00 | ALDH1A1 (0.66) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6589695 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KCNMA1NPC1RAB9AKDM4E | |
| SCHEMBL6589698 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KCNMA1NPC1RAB9AKDM4E | |
| SCHEMBL6589705 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KCNMA1NPC1RAB9AKDM4E | |
| SCHEMBL6079738 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6584488 | 0.84 | MAPK1 (0.50) | ALDH1A1NPC1RAB9AHTTGAA | |
| SCHEMBL6588460 | 0.84 | APP (0.59) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6584481 | 0.84 | MAPK1 (0.50) | ALDH1A1NPC1RAB9AHTTGAA | |
| SCHEMBL6588464 | 0.84 | APP (0.59) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |