Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588463 | 1.00 | APP (0.59) | APPKCNMA1L3MBTL1TRPV1PKM | |
| SCHEMBL6588460 | 1.00 | APP (0.59) | APPKCNMA1L3MBTL1TRPV1PKM | |
| SCHEMBL6080575 | 0.87 | APP (0.54) | APPKCNMA1L3MBTL1TRPV1PKM | |
| SCHEMBL6080567 | 0.87 | APP (0.54) | APPKCNMA1L3MBTL1TRPV1PKM | |
| SCHEMBL6584481 | 0.84 | MAPK1 (0.50) | APPPKMMEN1NPC1RAB9A | |
| SCHEMBL6584488 | 0.84 | MAPK1 (0.50) | APPPKMMEN1NPC1RAB9A | |
| SCHEMBL6587311 | 0.84 | ALDH1A1 (0.66) | KCNMA1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL6587318 | 0.84 | ALDH1A1 (0.66) | KCNMA1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL6587315 | 0.84 | ALDH1A1 (0.66) | KCNMA1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL6584485 | 0.84 | MAPK1 (0.50) | APPPKMMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |
| EP-0201203-A2 | Method of treatment of plants with aniline derivatives | MAY & BAKER LIMITED (GB) | 1986-11-12 | — | — | EP | disclosed |