SCHEMBL6584597

SCHEMBL6584597

CSC(=O)c1ccc(C)c(O)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KMT2A Q03164 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 1/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
PSMD14 O00487 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MMP2 P08253 1/20 0.32
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GRM1 Q13255 1/20 0.32
CYP1A2 P05177 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8309462 0.81 ALB (0.36) ALDH1A1HSD17B10KMT2AMEN1MAPT
SCHEMBL30988009 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL2500795 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL7049791 0.77 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL6582254 0.76 SMN1; SMN2 (0.37) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL29051212 0.74 CHRM1 (0.35) ALDH1A1HPGDKMT2ACYP3A4MEN1
SCHEMBL29026507 0.73 ESR1 (0.50) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL8679249 0.71 HTT (0.32) GAARAB9A
SCHEMBL29272521 0.69 ESR1 (0.46) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL23941175 0.69 TSHR (0.55) ALDH1A1KDM4EHSD17B10MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900795-B1 BENZENE DERIVATIVES SUBSTITUTED BY HETEROCYCLES AND HERBICIDES NIPPON SODA CO (JP) 2004-04-21 EP disclosed
US-6100421-A METHYL 3-FORMYL-4-METHANESULFONYL-2-METHYLBENZOATE, USEFUL AS A STARTING MATERIAL FOR HERBICIDE MANUFACTURE NIPPON SODA CO., LTD. (JP) 2000-08-08 US disclosed
US-5939360-A HERBICIDES WITH HYDROXYPYRAZOLEISOOXAZOLE KETONES NIPPON SODA CO., LTD. (JP) 1999-08-17 US disclosed
CN-1216543-A Heterocyclic substituted benzene derivatives and herbicides NIPPON SODA CO (JP) 1999-05-12 CN disclosed
EP-0900795-A1 BENZENE DERIVATIVES SUBSTITUTED BY HETEROCYCLES AND HERBICIDES NIPPON SODA CO., LTD. (JP) 1999-03-10 EP disclosed
EP-0894792-A1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVES AND HERBICIDES NIPPON SODA CO., LTD. (JP) 1999-02-03 EP disclosed
US-5834404-A Substituted bicycloheptanedione derivative and herbicide NIPPON SODA CO., LTD. (JP) 1998-11-10 US disclosed
EP-0791572-A1 SUBSTITUTED BICYCLOHEPTANEDIONE DERIVATIVE AND HERBICIDE NIPPON SODA CO., LTD. (JP) 1997-08-27 EP disclosed