SCHEMBL2500795

SCHEMBL2500795

Cc1ccc(C(=O)O)c(C)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 1/20 0.57
HPGD P15428 1/20 0.57
HSD17B10 Q99714 1/20 0.57
KMT2A Q03164 2/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
SELL P14151 1/20 0.46
SELP P16109 1/20 0.46
GRM1 Q13255 1/20 0.46
MAPT P10636 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 1/20 0.45
PSMD14 O00487 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MMP2 P08253 1/20 0.45
GAA P10253 1/20 0.45
THRB P10828 1/20 0.45
MAPK1 P28482 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30988009 1.00 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL857301 0.84 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL30083685 0.84 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL30589153 0.82 SELL (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL38623 0.82 SELL (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL317576 0.82 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL30149140 0.82 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL7049791 0.82 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL29370019 0.81 CYP1A2 (0.48) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL242262 0.81 CYP1A2 (0.48) ALDH1A1KDM4EHPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
CN-110277529-A A kind of high multiplying power lithium ion battery functional composite membrane and preparation method thereof 新乡市中科科技有限公司 2019-09-24 CN claimed
US-20150064274-A1 MICRONIZED PLACENTAL COMPOSITIONS COMPRISING A CHELATOR MIMEDX GROUP, INC. 2015-03-05 US disclosed
CN-102981368-B Antireflective film-forming composition containing vinyl ether compound NISSAN CHEMICAL IND LTD 2015-03-04 CN disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
EP-1813613-B1 NOVEL FUSED IMIDAZOLE DERIVATIVE MSD KK (JP) 2012-12-19 EP disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-8030327-B2 3-[1-(2-chlorophenyl)ethoxy]-5-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxyamide; polo like kinase inhibitor; antitumor and anticarcinogenic agent; mitotic phase (M phase) of the cell cycle MDS K.K. (JP) 2011-10-04 US disclosed
US-20080103136-A1 Novel Fused Imidazole Derivative MSD K.K. (JP) 2008-05-01 US disclosed
CN-101074242-A Cells accumulation for sphosphonate analogs of HIV protease inhibitor compound and the same compound GILEAD SCIENCES INC (US) 2007-11-21 CN disclosed
EP-1813613-A1 NOVEL FUSED IMIDAZOLE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-01 EP disclosed
CN-1649885-A Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds GILEAD SCIENCES INC (US) 2005-08-03 CN disclosed
US-6903079-B2 Nucleoside compounds and compositions thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2005-06-07 US disclosed
US-20030149050-A1 Inhibitors of inflammation and reperfusion injury and methods of use thereof INOTEK CORP. 2003-08-07 US disclosed
US-6534651-B2 Substituted isoindolinone derivatives INOTEK PHARMACEUTICALS CORP. 2003-03-18 US disclosed
US-20020095044-A1 Inhibitors of inflammation and reperfusion injury and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION 2002-07-18 US disclosed
WO-2001077075-A2 INHIBITORS OF INFLAMMATION AND REPERFUSION INJURY INOTEK CORPORATION (US) 2001-10-18 WO disclosed
EP-0083228-B1 PHARMACEUTICALLY ACTIVE PHENYLCARBOXYLIC ACID DERIVATIVES ICI AMERICAS INC. (US) 1985-05-15 EP disclosed
US-4499299-A Pharmaceutically active phenylcarboxylic acid derivatives ICI AMERICAS INC. (US) 1985-02-12 US disclosed
EP-0083228-A1 Pharmaceutically active phenylcarboxylic acid derivatives ICI AMERICAS INC. (US) 1983-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150064274-A1 MICRONIZED PLACENTAL COMPOSITIONS COMPRISING A CHELATOR ALPP, PGF, CD68 ALDH1A1 2511/4885KDM4E 2972/4885HPGD 434/4885
US-20020095044-A1 Inhibitors of inflammation and reperfusion injury and methods of use thereof IL1B, PTGS1, MMP8 ALDH1A1 210/4885KDM4E 4393/4885HPGD 92/4885
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 ALDH1A1 181/4885KDM4E 2650/4885HPGD 4150/4885
US-20080103136-A1 Novel Fused Imidazole Derivative HRH4, H1-4, H1-3 ALDH1A1 1939/4885KDM4E 1299/4885HPGD 2599/4885
US-20030149050-A1 Inhibitors of inflammation and reperfusion injury and methods of use thereof IL1B, PTGS1, MMP8 ALDH1A1 210/4885KDM4E 4393/4885HPGD 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.