Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460896 | 0.87 | BCHE (0.59) | ACHEBCHEBACE1SMN1; SMN2SIGMAR1 | |
| SCHEMBL13460892 | 0.81 | BCHE (0.58) | ACHEBCHEBACE1SIGMAR1MEN1 | |
| SCHEMBL22713946 | 0.80 | ALDH1A1 (0.68) | — | |
| SCHEMBL6584176 | 0.79 | ACHE (0.52) | ACHEBCHESIGMAR1 | |
| SCHEMBL6883557 | 0.79 | ALDH1A1 (0.66) | — | |
| SCHEMBL21306436 | 0.78 | SMN1; SMN2 (0.55) | ACHEBCHEBACE1SMN1; SMN2SIGMAR1 | |
| SCHEMBL70835 | 0.77 | ALDH1A1 (0.64) | — | |
| SCHEMBL29808190 | 0.77 | ALDH1A1 (0.64) | — | |
| SCHEMBL7560477 | 0.77 | ALDH1A1 (0.64) | — | |
| SCHEMBL6583476 | 0.77 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |