Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.61 |
| ▸ | PDE4A | P27815 | 6/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764133 | 0.90 | PDE4B (0.75) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL7763217 | 0.90 | PDE4B (0.75) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL6584071 | 0.87 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL6582993 | 0.84 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL6584651 | 0.83 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7170196 | 0.83 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL7170264 | 0.83 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL7171526 | 0.83 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL6585357 | 0.81 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6588290 | 0.79 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |