Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.75 |
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763217 | 1.00 | PDE4B (0.75) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL6584640 | 0.90 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CALOX15 | |
| SCHEMBL7764115 | 0.88 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CIGF1R | |
| SCHEMBL7760278 | 0.88 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CIGF1R | |
| SCHEMBL7763958 | 0.88 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CIGF1R | |
| SCHEMBL11435807 | 0.87 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| Daxalipram SCHEMBL450824 | 0.86 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CFPR2 | |
| Daxalipram SCHEMBL7760245 | 0.86 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CFPR2 | |
| Daxalipram SCHEMBL450823 | 0.86 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CFPR2 | |
| SCHEMBL8486179 | 0.85 | PDE4B (0.67) | PDE4BPDE4DPDE4APDE4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859766-B1 | CHIRAL METHYL PHENYL OXAZOLIDINONES | SCHERING AG (DE) | 2001-05-16 | — | — | EP | claimed |
| US-6025376-A | INHIBITORS OF TUMOR NECROSIS FACTOR, TREATING MULTIPLE SCLEROSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |