Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 8/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582993 | 0.87 | PDE4B (0.71) | PDE4BPDE4DLMNAKMT2APDE4A | |
| SCHEMBL6584640 | 0.87 | PDE4B (0.61) | PDE4BPDE4DCBLBKMT2APDE4A | |
| SCHEMBL6585249 | 0.87 | PDE4B (0.56) | PDE4BPDE4DLMNAKMT2APDE4A | |
| SCHEMBL6584651 | 0.86 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL11435807 | 0.86 | PDE4B (0.77) | PDE4BPDE4DLMNAMAOAKMT2A | |
| SCHEMBL6586396 | 0.84 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6585357 | 0.83 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6585598 | 0.81 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7172425 | 0.78 | LMNA (0.48) | PDE4BPDE4DLMNAMAOAKMT2A | |
| SCHEMBL7172429 | 0.78 | LMNA (0.48) | PDE4BPDE4DLMNAMAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |