Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584909 | 0.99 | ALDH1A1 (0.58) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL9733843 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL498127 | 0.95 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL30352601 | 0.95 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL2843045 | 0.92 | FDPS (0.61) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL637014 | 0.90 | FDPS (0.67) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL5451218 | 0.84 | HPGD (0.59) | ALDH1A1TSHRPDE4BFDPSALDH1A3 | |
| SCHEMBL6585016 | 0.83 | FDPS (0.62) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL1299518 | 0.83 | HPGD (0.59) | ALDH1A1TSHRFDPSSMN1; SMN2LMNA | |
| SCHEMBL14834850 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRPDE4BFDPSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |