Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.55 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584909 | 0.99 | ALDH1A1 (0.58) | ALDH1A1TSHRPDE4BFDPSLMNA | |
| SCHEMBL6584890 | 0.97 | ALDH1A1 (0.60) | ALDH1A1TSHRPDE4BFDPSLMNA | |
| SCHEMBL2843045 | 0.94 | FDPS (0.61) | ALDH1A1TSHRPDE4BFDPSLMNA | |
| SCHEMBL498127 | 0.93 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BFDPSLMNA | |
| SCHEMBL30352601 | 0.93 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BFDPSLMNA | |
| SCHEMBL637014 | 0.87 | FDPS (0.67) | ALDH1A1TSHRPDE4BFDPSLMNA | |
| SCHEMBL1299518 | 0.86 | HPGD (0.59) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL4177854 | 0.84 | HPGD (0.63) | ALDH1A1PDE4BFDPSPARP15PARP10 | |
| SCHEMBL9122043 | 0.83 | KMT2A (0.47) | ALDH1A1TSHRPDE4BFDPSMAPT | |
| SCHEMBL3685060 | 0.82 | HPGD (0.49) | ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135955-A | Anticoagulants or antifungal activity | ELI LILLY AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0339878-A2 | Propanamine derivatives | ELI LILLY AND COMPANY (US) | 1989-11-02 | — | — | EP | disclosed |