SCHEMBL65853

SCHEMBL65853

O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.49
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP14 P50281 1/20 0.46
KIF11 P52732 1/20 0.46
NOD1 Q9Y239 1/20 0.46
PTGS2 P35354 3/20 0.45
PTGS1 P23219 1/20 0.45
EPHX2 P34913 1/20 0.44
FBP1 P09467 1/20 0.44
HTR2A P28223 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL26923048 0.98 FFAR4 (0.47) FFAR4BCHEACHEMMP2MMP9
SCHEMBL3310741 0.94 MMP9 (0.54) FFAR4BCHEACHEMMP2MMP9
SCHEMBL21556097 0.84 ALDH1A1 (0.40) FFAR4BCHEACHEMMP2MMP9
SCHEMBL6632895 0.82 ALDH1A1 (0.39) FFAR4BCHEACHEMMP2MMP9
SCHEMBL1489401 0.82 TRPV1 (0.40) FFAR4BCHEACHEMMP2MMP9
SCHEMBL11683700 0.81 ALDH1A1 (0.38) FFAR4BCHEACHEMMP2MMP9
SCHEMBL13542559 0.81 FFAR4 (0.50) FFAR4BCHEACHEMMP2MMP9
SCHEMBL27245279 0.81 TRPV1 (0.68) EPHX2
SCHEMBL24903837 0.80 FFAR4 (0.47) FFAR4BCHEACHEMMP2MMP9
SCHEMBL4190483 0.79 FFAR4 (0.38) FFAR4BCHEACHEMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522575-B2 2-diarylmethyl-4-aminotetrahydropyran derivatives and related compounds as anticancer, antiinflammatory, antifibrotic and neuroprotective agents ATUX ISKAY LLC (US) 2026-01-13 US claimed
US-20250376455-A1 2-DIARYLMETHYL-4-AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS ATUX ISKAY LLC (US) 2025-12-11 US claimed
CN-120082181-A PBAT/bamboo powder biodegradable composite master batch, preparation method thereof and composite film 国际竹藤中心 2025-06-03 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-113173891-A Molecular probe derived from calcium-sensitive receptor protein antagonist and application of molecular probe in parathyroidectomy 大连医科大学附属第二医院 2021-07-27 CN claimed
CN-109608369-B Sulfonyl ester group anthraquinone derivative and preparation method and application thereof 广西大学 2021-04-09 CN claimed
CN-110452146-A Trifluoromethyl seleno-amino acids derivative and preparation method thereof UNIV WUHAN TECH 2019-11-15 CN claimed
CN-109608369-A Sulphonyl ester group anthraquinone derivatives and its preparation method and application 广西大学 2019-04-12 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-6713220-B2 RESISTANCE TO LIGHT SHOCK; CHARGE TRANSPORT LAYER CONTAINS DIPHENOQUINONE 3,3',5,5'-TETRA-TERT-BUTYL-4,4'-DIPHENOQUINONE TO ABSORB LIGHT OF WAVELENGTH LESS THAN 700 NM; PHOTOGENERATOR IS A HYDROXYGALLIUM PHTHALOCYANINE XEROX CORPORATION 2004-03-30 US claimed
CN-122080012-A Thienopyrimidine derivative, preparation method, application and pharmaceutical composition thereof 2026-05-26 CN disclosed
CN-122079918-A Isoxazole biphenyl compounds with CBP BRD and BRD4 BD2 inhibitory activity, and preparation method and application thereof 2026-05-26 CN disclosed
EP-4741018-A2 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-05-13 EP disclosed
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CHEMOCENTRYX, INC. (US) 2026-04-28 US disclosed
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 US disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed
WO-1996025934-A1 ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1996-08-29 WO disclosed
EP-0659181-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1995-06-28 EP disclosed
CN-1087347-A The new sulfonamide inhibitors of aspartyl protease VERTEX PHARMA (US) 1994-06-01 CN disclosed
WO-1994005639-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CCR1, CCR9, CCR8 FFAR4 227/4885BCHE 2992/4885ACHE 4877/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 FFAR4 212/4885BCHE 1834/4885ACHE 4044/4885
US-20250376455-A1 2-DIARYLMETHYL-4-AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS MYC, MYCBP, MYCBP2 FFAR4 3864/4885BCHE 4364/4885ACHE 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.