Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294106 | 0.79 | MAOB (0.61) | MEN1ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL30718037 | 0.77 | ALDH1A1 (0.54) | MEN1ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL643543 | 0.77 | ALDH1A1 (0.54) | MEN1ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL1036450 | 0.77 | KCNA5 (0.53) | MAOB | |
| SCHEMBL6174918 | 0.76 | CYP19A1 (0.52) | MEN1ALDH1A1KMT2ALMNAHTT | |
| SCHEMBL27237001 | 0.76 | MAOB (0.69) | HRH3MAOBMAOA | |
| SCHEMBL5247803 | 0.75 | MAOB (0.49) | HRH3MAOBMAOA | |
| SCHEMBL1037269 | 0.74 | DRD2 (0.56) | HRH3 | |
| SCHEMBL1377016 | 0.74 | MAOB (0.69) | HRH3MAOBMAOA | |
| SCHEMBL6294041 | 0.74 | ALDH1A1 (0.58) | MEN1ALDH1A1HPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0905134-B1 | Piperidine derivatives as LTD4 and H1 antagonists | KOWA CO (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-6107308-A | ANTIHISTAMINE; LEUTRIENE ANTAGONIST | KOWA CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0905134-A1 | Piperidine derivatives as LTD4 and H1 antagonists | KOWA COMPANY, LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |