Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585566 | 0.89 | ALDH1A1 (0.54) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6960793 | 0.87 | HPGD (0.56) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6581254 | 0.84 | ALDH1A1 (0.37) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6960790 | 0.84 | MEN1 (0.58) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6965868 | 0.83 | ALDH1A1 (0.65) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6965864 | 0.83 | ALDH1A1 (0.65) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6972867 | 0.79 | ALDH1A1 (0.64) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL8337333 | 0.78 | ALDH1A1 (0.65) | KDM4EHPGDALDH1A1MAPTKCNH2 | |
| SCHEMBL8337336 | 0.78 | ALDH1A1 (0.65) | KDM4EHPGDALDH1A1MAPTKCNH2 | |
| SCHEMBL6961283 | 0.75 | KDM4E (0.81) | KDM4EHPGDALDH1A1MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |