Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24697057 | 0.95 | FDPS (0.71) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL752160 | 0.88 | ALDH1A1 (0.65) | FDPSALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29377794 | 0.88 | ALDH1A1 (0.65) | FDPSALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6229249 | 0.85 | FDPS (0.63) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL7661907 | 0.84 | FDPS (0.86) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL13727944 | 0.84 | ALDH1A1 (0.54) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL19658009 | 0.83 | FDPS (0.65) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL15952102 | 0.83 | TACR2 (0.60) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL15952860 | 0.83 | FDPS (0.60) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL7545268 | 0.83 | MAPT (0.60) | FDPSALDH1A1MAPTHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5747506-A | Isoquinoline compounds, compositions containing them and their pharmaceutical uses | NOVARTIS AG (CH) | 1998-05-05 | — | — | US | disclosed |
| EP-0664289-A2 | Isoquinolines | SANDOZ LTD. (CH) | 1995-07-26 | — | — | EP | disclosed |