Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 9/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152411 | 0.89 | LMNA (0.45) | GRM2KDM4ELMNAALDH1A1POLB | |
| SCHEMBL6585504 | 0.87 | POLB (0.35) | GRM2KDM4EOPRM1OPRD1LMNA | |
| SCHEMBL6585292 | 0.84 | HTR1A (0.42) | DRD4DRD2MAPT | |
| SCHEMBL6584451 | 0.83 | HTR1A (0.37) | DRD2DRD3MAPT | |
| SCHEMBL6584265 | 0.82 | HTR1A (0.40) | DRD2MAPT | |
| SCHEMBL6585830 | 0.82 | HTR1A (0.42) | DRD2MAPT | |
| SCHEMBL6584859 | 0.81 | HTR1A (0.41) | DRD2MAPT | |
| SCHEMBL8152413 | 0.80 | HTR1A (0.33) | KDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL6584452 | 0.80 | MEN1 (0.46) | DRD2DRD3MAPT | |
| SCHEMBL8309662 | 0.80 | HTR1A (0.40) | DRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |