Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 10/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581080 | 0.87 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 | |
| SCHEMBL6586242 | 0.86 | HTR1A (0.53) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 | |
| SCHEMBL6586238 | 0.85 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 | |
| SCHEMBL547419 | 0.77 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 | |
| SCHEMBL6585806 | 0.75 | KCNH2 (0.57) | HTR1ASLC6A4HTR6 | |
| SCHEMBL6582893 | 0.74 | HTR6 (0.56) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 | |
| SCHEMBL6584644 | 0.73 | KCNH2 (0.63) | HTR1ASLC6A4HTR6 | |
| SCHEMBL547695 | 0.73 | HTR1A (0.71) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 | |
| SCHEMBL5372329 | 0.72 | HTR6 (0.73) | HTR1AHTR6ADRB1HTR3A | |
| Hydrochloric Acid SCHEMBL4931243 | 0.71 | HTR6 (0.59) | HTR1ASLC6A2SLC6A4HTR6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246815-B1 | PHENYLPIPERAZINYL DERIVATIVES | LUNDBECK & CO AS H (DK) | 2004-03-17 | — | — | EP | disclosed |
| US-20030083336-A1 | Phenylpiperazinyl derivatives | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083336-A1 | Phenylpiperazinyl derivatives | DRD4, DRD2, DRD3 | HTR1A 24/4885SLC6A2 157/4885SLC6A4 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.