Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 8/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587898 | 0.87 | QDPR (0.60) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL7305529 | 0.83 | QDPR (0.76) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL6590672 | 0.82 | QDPR (0.54) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL6584948 | 0.82 | SIGMAR1 (0.65) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL17548153 | 0.82 | QDPR (0.70) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL12479331 | 0.80 | QDPR (0.72) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL10407313 | 0.79 | QDPR (1.00) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL3961889 | 0.79 | SIGMAR1 (0.65) | QDPRSIGMAR1HTR2CHTR7HTR6 | |
| SCHEMBL27553177 | 0.79 | QDPR (0.70) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL3899585 | 0.77 | SIGMAR1 (0.92) | QDPRSIGMAR1HTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |