Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343066 | 0.88 | UBE2M (0.41) | DPP4KCNH2DPP7RAB9ATSHR | |
| SCHEMBL7338294 | 0.74 | SMN1; SMN2 (0.34) | DPP4KCNH2DPP7NPC1RAB9A | |
| SCHEMBL24974571 | 0.66 | HRH3 (0.49) | KCNH2NPC1RAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL6584997 | 0.66 | UBE2M (0.35) | DPP4KCNH2DPP7NPC1RAB9A | |
| SCHEMBL21274786 | 0.63 | DPP4 (0.55) | DPP4KCNH2DPP7NPC1RAB9A | |
| SCHEMBL21274787 | 0.63 | DPP4 (0.55) | DPP4KCNH2DPP7NPC1RAB9A | |
| SCHEMBL24297824 | 0.63 | ALDH1A1 (0.53) | NPC1RAB9ASLC6A3L3MBTL1 | |
| SCHEMBL28973567 | 0.63 | ALDH1A1 (0.53) | NPC1RAB9ASLC6A3L3MBTL1 | |
| SCHEMBL19876581 | 0.62 | SMN1; SMN2 (0.66) | LNPEPNPC1RAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL17946175 | 0.62 | SMN1; SMN2 (0.66) | LNPEPNPC1RAB9ASMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815080-B1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-06-16 | — | — | EP | disclosed |
| US-6002009-A | Di-substituted 1,4-piperidine esters and amides having 5-HT4 antagonistic activity | BOEHRINGER INGELHEIM ITALIA, S.P.A. (IT) | 1999-12-14 | — | — | US | disclosed |
| WO-1996028424-A1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1996-09-19 | — | — | WO | disclosed |