SCHEMBL658632

SCHEMBL658632

CC(=O)NC1CCC(=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 4/20 0.50
MTNR1B P49286 4/20 0.50
TLR4 O00206 1/20 0.50
ATM Q13315 1/20 0.45
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALOX15 P16050 1/20 0.37
DRD2 P14416 1/20 0.36
KDM1A O60341 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4420636 0.87 MTNR1A (0.56) MTNR1AMTNR1BTLR4ATMALDH1A1
Acetic Acid SCHEMBL28266825 0.83 TLR4 (0.37) MTNR1AMTNR1BTLR4ALDH1A1KDM4E
SCHEMBL5949519 0.82 MTNR1A (0.50) MTNR1AMTNR1BTLR4ATMALDH1A1
SCHEMBL14720508 0.82 MTNR1A (0.50) MTNR1AMTNR1BTLR4ATMALDH1A1
SCHEMBL14274551 0.80 MTNR1A (0.49) MTNR1AMTNR1BTLR4ATMALDH1A1
SCHEMBL50350 0.80
SCHEMBL284319 0.80 ATM (0.56) MTNR1AMTNR1BTLR4ATMALDH1A1
SCHEMBL284342 0.80 ATM (0.56) MTNR1AMTNR1BTLR4ATMALDH1A1
SCHEMBL284318 0.80 ATM (0.56) MTNR1AMTNR1BTLR4ATMALDH1A1
SCHEMBL743138 0.79 EPHX1 (0.36) TLR4ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325219-A Flame-retardant cable 中迈电线电缆有限公司 2024-07-12 CN claimed
CN-115029401-A Method for co-production of fulvic acid organic fertilizer by straw sugar production 蚌埠星河秸秆生物科技有限公司 2022-09-09 CN claimed
CN-115029391-A Fermentation method for producing lactic acid by using mixed sugar as carbon source 安徽丰原集团有限公司 2022-09-09 CN claimed
CN-216778796-U Cyclization device for producing (R) -3-amino-1, 2,3, 4-tetrahydrocarbazole 福建福瑞明德药业有限公司 2022-06-21 CN claimed
CN-111748048-B Preparation method of modified chitosan acidizing corrosion inhibitor 西南石油大学 2020-12-11 CN claimed
CN-111748048-A Preparation method of modified chitosan acidizing corrosion inhibitor 西南石油大学 2020-10-09 CN claimed
CN-111362884-A Industrial preparation method of 2, 6-diamino-4, 5,6, 7-tetrahydro-benzothiazole 江苏神龙药业股份有限公司 2020-07-03 CN claimed
CN-111018805-A Synthesis and separation method of pramipexole intermediate 江苏汉斯通药业有限公司 2020-04-17 CN claimed
CN-107417705-B Imidazo [2,1-b] benzothiazole compound and its synthetic method 湘潭大学 2019-07-02 CN claimed
WO-2019016828-A1 NOVEL PROCESSES FOR THE PREPARATION OF TRANS-N-{4-[2-[4-(2,3-DICHLOROPHENYL)PIPERAZINE-1-YL]ETHYL] CYCLOHEXYL}-N',N'-DIMETHYLUREA HYDROCHLORIDE AND POLYMORPHS THEREOF MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2019-01-24 WO claimed
WO-2011021214-A2 IMPROVED PROCESS FOR THE PREPARATION OF (S)-2-AMINO-4,5,6,7-TETRAHYDRO-6 - (PROPYLAMINO) BENZOTHIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2011-02-24 WO claimed
WO-2008104847-A2 PROCESSES FOR THE PREPARATION OF PRAMIPEXOLE AND SALTS THEREOF WOCKHARDT RESEARCH CENTRE (IN) 2008-09-04 WO claimed
EP-1562921-B1 PROCESS FOR PREPARING 2,6-DIAMINO-4,5,6,7-TETRAHYDRO-BENZOTHIAZOLE CIPLA LTD (IN) 2008-05-21 EP claimed
US-7285669-B2 Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole CIPLA LIMITED (IN) 2007-10-23 US claimed
US-20060100256-A1 Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole CIPLA LIMITED (IN) 2006-05-11 US claimed
EP-1562921-A1 PROCESS FOR PREPARING 2,6-DIAMINO-4,5,6,7-TETRAHYDRO-BENZOTHIAZOLE Cipla Ltd. (IN) 2005-08-17 EP claimed
WO-2004041797-A1 PROCESS FOR PREPARING 2,6-DIAMINO-4,5,6,7-TETRAHYDRO-BENZOTHIAZOLE CIPLA LTD (IN) 2004-05-21 WO claimed
US-20260146043-A1 CRYSTALLINE FORMS OF PYRIMIDINO DIAZEPINE DERIVATIVE CYCLACEL PHARMACEUTICALS INC. (US) 2026-05-28 US disclosed
US-3960945-A 4-[-(Alkoxy or polyhaloalkoxy)-benzamido]cyclohexanones STERLING DRUG INC. (US) 1976-06-01 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146043-A1 CRYSTALLINE FORMS OF PYRIMIDINO DIAZEPINE DERIVATIVE CTNND1, CCNC, SFN MTNR1A 3144/4885MTNR1B 2186/4885TLR4 3303/4885
US-20060100256-A1 Process for preparing 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole DNPEP, DDO, HNMT MTNR1A 3786/4885MTNR1B 2182/4885TLR4 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.