Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.50 |
| ▸ | PDE4A | P27815 | 17/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585249 | 0.86 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6584071 | 0.84 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6584367 | 0.80 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7916424 | 0.79 | PDE4B (0.49) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6584651 | 0.77 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6585357 | 0.76 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6582993 | 0.75 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6584640 | 0.75 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7763968 | 0.75 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7764127 | 0.75 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| JP-2004002256-A | OPTICALLY ACTIVE OXAZINE DERIVATIVE | NIKKEN CHEM CO LTD | 2004-01-08 | — | — | JP | disclosed |
| WO-2003008396-A1 | OPTICALLY ACTIVE OXAZINE DERIVATIVE | NIKKEN CHEMICALS CO., LTD. (JP) | 2003-01-30 | — | — | WO | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |