Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582744 | 0.89 | SIGMAR1 (0.50) | SIGMAR1EBPTMEM97 | |
| SCHEMBL7906172 | 0.84 | NFKB1 (0.53) | FFAR1FFAR4PPARDPPARASIGMAR1 | |
| SCHEMBL6586912 | 0.82 | PDE4B (0.46) | PPARDPPARAPDE4APDE4BPDE4C | |
| SCHEMBL6582898 | 0.81 | PPARG (0.53) | PPARDPPARAKMT2APDE4APDE4B | |
| SCHEMBL6583680 | 0.79 | PDE4B (0.42) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL6588285 | 0.78 | HIF1A (0.45) | PPARDPPARAKMT2APDE4APDE4B | |
| SCHEMBL6584079 | 0.77 | PDE4B (0.43) | SIGMAR1EBPTMEM97KMT2APDE4A | |
| SCHEMBL6585940 | 0.77 | L3MBTL1 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6584988 | 0.77 | CHEK1 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6586764 | 0.77 | PDE4B (0.46) | PPARDPPARAPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |