Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.59 |
| ▸ | MMP3 | P08254 | 13/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590191 | 0.93 | MMP2 (0.63) | MMP2MMP3L3MBTL1PKM | |
| SCHEMBL6583989 | 0.91 | MMP2 (0.60) | MMP2MMP3L3MBTL1PKMEPHX1 | |
| SCHEMBL6584779 | 0.91 | MMP2 (0.65) | MMP2MMP3L3MBTL1CYP3A4CYP2C9 | |
| SCHEMBL6585027 | 0.90 | MMP2 (0.51) | MMP2MMP3L3MBTL1CYP3A4CYP2C9 | |
| SCHEMBL6584009 | 0.90 | MMP2 (0.64) | MMP2MMP3L3MBTL1ADAM10MMP1 | |
| SCHEMBL6582503 | 0.89 | MMP2 (0.55) | MMP2MMP3CYP3A4CYP2C9PKM | |
| SCHEMBL6582426 | 0.88 | MMP2 (0.66) | MMP2MMP3CYP3A4CYP2C9PKM | |
| SCHEMBL6433272 | 0.87 | MMP2 (0.44) | MMP2MMP3L3MBTL1CYP3A4CYP2C9 | |
| SCHEMBL6584555 | 0.85 | MMP2 (0.63) | MMP2MMP3L3MBTL1ADAM10MMP9 | |
| SCHEMBL6586078 | 0.83 | MMP2 (0.64) | MMP2MMP3L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |