Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.55 |
| ▸ | MMP3 | P08254 | 11/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582426 | 0.92 | MMP2 (0.66) | MMP2MMP3CCNT1CDK9CYP3A4 | |
| SCHEMBL6584396 | 0.92 | MMP2 (0.54) | MMP2MMP3CCNT1CDK9ADAM10 | |
| SCHEMBL6586008 | 0.91 | MMP2 (0.58) | MMP2MMP3CCNT1CDK9ADAM10 | |
| SCHEMBL6586997 | 0.89 | MMP2 (0.59) | MMP2MMP3CYP3A4CYP2C9PKM | |
| SCHEMBL6584779 | 0.85 | MMP2 (0.65) | MMP2MMP3CCNT1CDK9CYP3A4 | |
| SCHEMBL6588431 | 0.84 | MMP2 (0.66) | MMP2MMP3CCNT1CDK9ADAM10 | |
| SCHEMBL6588157 | 0.84 | MMP2 (0.70) | MMP2MMP3CCNT1CDK9ADAM10 | |
| SCHEMBL6433272 | 0.84 | MMP2 (0.44) | MMP2MMP3CYP3A4CYP2C9PKM | |
| SCHEMBL6590191 | 0.82 | MMP2 (0.63) | MMP2MMP3PKM | |
| SCHEMBL6583989 | 0.80 | MMP2 (0.60) | MMP2MMP3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |