Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482332 | 0.92 | DHODH (0.43) | PARP1DHODHHPSEALOX15PTGS1 | |
| SCHEMBL6584238 | 0.89 | PARP1 (0.49) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6805307 | 0.84 | PARP1 (0.65) | PARP1DHODHCHEK2 | |
| SCHEMBL6588332 | 0.82 | PARP1 (0.42) | PARP1DHODHHPSECHEK2PLA2G2A | |
| SCHEMBL6586846 | 0.77 | PARP1 (0.46) | PARP1DHODHCHEK2 | |
| SCHEMBL7471031 | 0.76 | PARP1 (0.45) | PARP1DHODHHPSECHEK2 | |
| SCHEMBL6590617 | 0.75 | PARP1 (0.48) | PARP1DHODHHPSECHEK2 | |
| SCHEMBL6592136 | 0.74 | PARP1 (0.43) | PARP1DHODHHPSEPLA2G2AALOX15 | |
| SCHEMBL6590776 | 0.74 | PARP1 (0.46) | PARP1DHODHHPSECHEK2ALOX15 | |
| SCHEMBL6804274 | 0.73 | PARP1 (0.69) | PARP1DHODHCHEK2PLA2G2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |