SCHEMBL6587262

SCHEMBL6587262

CC1C=C(COS(C)(=O)=O)CCC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6588086 0.73 ALDH1A1 (0.46) ALDH1A1ALOX15
SCHEMBL2588454 0.72 ALDH1A1 (0.53) ALDH1A1ALOX15
SCHEMBL6583388 0.70 ALDH1A1 (0.51) ALDH1A1ALOX15
SCHEMBL6583396 0.70 ALDH1A1 (0.51) ALDH1A1ALOX15
SCHEMBL4442242 0.70
SCHEMBL6593555 0.70 CES2 (0.32)
SCHEMBL6589241 0.69 CYP2D6 (0.39) ALDH1A1
SCHEMBL3862032 0.69 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3862038 0.69 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3862034 0.68 EPHX1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823423-B1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMA CO LTD (JP) 2004-06-16 EP disclosed
US-5750540-A SIDE EFFECT REDUCTION BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0823423-A1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed